منابع مشابه
Ultrasound-induced Coalescence of Contrast Agent Microbubbles
ULTRASOUND-INDUCED COALESCENCE OF CONTRAST AGENT MICROBUBBLES M. POSTEMA*1,2, C. T. LANCÉE1, N. DE JONG1,3, P. MARMOTTANT3, and S. HILGENFELDT3, 1Dept. of Experimental Echocardiography, Thoraxcentre, Erasmus MC, 2Interuniversity Cardiology Institute of The Netherlands, 3Physics of Fluids, Dept. of Applied Physics, Faculty of Science and Technology, University of Twente. Corresponding e-mail: po...
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BACKGROUND Ultrasound and microbubbles (USMB) have been shown to enhance the intracellular uptake of molecules, generally thought to occur as a result of sonoporation. The underlying mechanism associated with USMB-enhanced intracellular uptake such as membrane disruption and endocytosis may also be associated with USMB-induced release of cellular materials to the extracellular milieu. This stud...
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The introduction of microbubbles in focused ultrasound therapies has enabled a diverse range of non-invasive technologies: sonoporation to deliver drugs into cells, sonothrombolysis to dissolve blood clots, and blood-brain barrier opening to deliver drugs into the brain. Current methods for passively monitoring the microbubble dynamics responsible for these therapeutic effects can identify the ...
متن کاملMicrobubble ultrasound contrast agents: a review.
The superior scattering properties of gas bubbles compared with blood cells have made microbubble ultrasound contrast agents important tools in ultrasound diagnosis. Over the past 2 years they have become the focus of a wide and rapidly expanding field of research, with their benefits being repeatedly demonstrated, both in ultrasound image enhancement, and more recently in drug and gene deliver...
متن کاملA Targeting Microbubble for Ultrasound Molecular Imaging
RATIONALE Microbubbles conjugated with targeting ligands are used as contrast agents for ultrasound molecular imaging. However, they often contain immunogenic (strept)avidin, which impedes application in humans. Although targeting bubbles not employing the biotin-(strept)avidin conjugation chemistry have been explored, only a few reached the stage of ultrasound imaging in vivo, none were report...
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ژورنال
عنوان ژورنال: Ultrasound in Medicine & Biology
سال: 2004
ISSN: 0301-5629
DOI: 10.1016/j.ultrasmedbio.2004.08.008